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Biopharma Report

Q4 2023

Biopharma Report

March 4, 2024

This report was reuploaded on May 6, 2024, to fix a typo on page 5.

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Biopharma investors focus on quality over quantity 

Despite a 19% quarter-over-quarter decline in deal value in Q4, investor enthusiasm for the biopharma industry is holding strong, particularly for companies integrating AI into drug discovery and those developing weight loss drugs. 

Meanwhile, a steady flow of exits returned $18.3 billion to VCs in 2023, the result of an increasingly selective investment approach driven by strong clinical data and recalibrating technology platform investment interest, writes Senior Analyst Kazi Helal. 

Our latest Emerging Tech Research unpacks recent VC trends across the biopharma industry, spotlights key players, and highlights emerging opportunities in molecular glue degraders, epigenetic editing, and macrocyclic peptides. 

Table of contents
Vertical update 3
Q4 2023 timeline 5
Biopharma landscape 6
Biopharma VC ecosystem market map 7
VC activity 9
Emerging opportunities 18
        Molecular glue degraders 19
        Epigenetic editing 20
        Macrocyclic peptides 21
Select company highlights 22
        Nimbus Therapeutics 23
        Generate:Biomedicines 26
        BioAge Labs 28