Spruce Biosciences Overview

  • Year Founded
  • 2016

Year Founded

  • Status
  • Public

  • Employees
  • 25

Employees

  • Stock Symbol
  • SPRB

Stock Symbol

  • Share Price
  • $0.07
  • (As of Monday Closing)

Spruce Biosciences General Information

Description

Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The pipeline products of the company include Tralesinidase Alfa (TA-ERT), and Tildacerfont/ Cortibon, a Companion Diagnostic, developed in partnership with HMNC Brain Health.

Contact Information

Website
sprucebio.com
Ownership Status
Publicly Held
Financing Status
Formerly VC-backed
Corporate Office
  • 611 Gateway Boulevard
  • Suite 740
  • South San Francisco, CA 94080
  • United States
+1 (415)
Primary Industry
Biotechnology
Other Industries
Drug Discovery
Stock Exchange
PINX
Vertical(s)
Corporate Office
  • 611 Gateway Boulevard
  • Suite 740
  • South San Francisco, CA 94080
  • United States
+1 (415)

Want detailed data on 3M+ companies?

What you see here scratches the surface

Request a free trial

Want to dig into this profile?

We’ll help you find what you need

Learn more

Spruce Biosciences Stock Performance

As of 07-Jul-2025, Spruce Biosciences’s stock price is $0.07. Its current market cap is $2.96M with 42.2M shares.

(As of Monday Closing)

Stock Price Previous Close 52 wk Range Market Cap Shares Average Volume EPS
$0.07 $0.07 $0.06 - $0.61 $2.96M 42.2M 1.43M -$1.32

Spruce Biosciences Financials Summary

As of 31-Mar-2025, Spruce Biosciences has a trailing 12-month revenue of $2.91M.

In Thousands,
USD
TTM 31-Mar-2025 FY 2024 31-Dec-2024 FY 2023 31-Dec-2023 FY 2022 31-Dec-2022
EV (44,843) (39,478) 16,312 (58,256)
Revenue 2,909 4,911 10,089 0
EBITDA (57,973) (56,105) (51,923) (47,209)
Net Income (55,452) (53,036) (47,919) (46,180)
Total Assets 31,649 45,209 103,946 85,648
Total Debt 2,295 2,765 4,609 6,315
Public Fundamental Data provided by Morningstar, Inc. disclaimer

Spruce Biosciences Valuation & Funding

Deal Type Date Amount Valuation/
EBITDA
Post-Val Status Debt

This information is available in the PitchBook Platform. To explore Spruce Biosciences‘s full profile, request access.

Request a free trial

Spruce Biosciences Cap Table

Stock # of Shares
Authorized
Par Value Dividend Rate (%) Original
Issue Price
Liquidation Liquidation
Pref. Multiple
Conversion
Price
% Owned

This information is available in the PitchBook Platform. To explore Spruce Biosciences‘s full profile, request access.

Request a free trial

Spruce Biosciences Comparisons

Description
Primary
Industry
HQ Location
Employees
Total Raised
Post Valuation
Last
Financing
Details
Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapi
Biotechnology
South San Francisco, CA
25 As of 2025

San Diego, CA
 

Boston, MA
 
Add Comparison

PitchBook’s comparison feature gives you a side-by-side look at key metrics for similar companies. Personalize which data points you want to see and create visualizations instantly.

Request a free trial

Spruce Biosciences Competitors (3)

One of Spruce Biosciences’s 3 competitors is Crinetics Pharmaceuticals, a Formerly VC-backed company based in San Diego, CA.

Company Name Financing Status Location Employees Total Raised Last Financing Date/Type Last Financing Amount
Crinetics Pharmaceuticals Formerly VC-backed San Diego, CA
Gelesis Holdings Formerly VC-backed Boston, MA
Ascendis Pharma Formerly VC-backed Hellerup, Denmark
You’re viewing 3 of 3 competitors. Get the full list »

Spruce Biosciences Patents

Spruce Biosciences Recent Patent Activity

Publication ID Patent Title Status First Filing Date Technology (CPC) Citations
CA-3235958-A1 Crystalline composition of tildacerfont and methods of use and preparation thereof Pending 19-Nov-2021
EP-4402142-A1 Crystalline composition of tildacerfont and methods of use and preparation thereof Pending 19-Nov-2021
US-11708372-B2 Crystalline composition of tildacerfont and methods of use and preparation thereof Active 19-Nov-2021
US-20230159533-A1 Crystalline composition of tildacerfont and methods of use and preparation thereof Active 19-Nov-2021
US-20240043432-A1 Crystalline composition of tildacerfont and methods of use and preparation thereof Inactive 19-Nov-2021 C07D487/04
To view Spruce Biosciences’s complete patent history, request access »

Spruce Biosciences Signals

Growth Rate

Weekly
Growth
Weekly Growth

Size Multiple

Median
Size Multiple

Key Data Points

Similarweb Unique Visitors

Majestic Referring Domains

PitchBook’s non-financial metrics help you gauge a company’s traction and growth using web presence and social reach.

Request a free trial

Spruce Biosciences Investors

Investor Name Investor Type Holding Investor Since Participating Rounds Contact Info

This information is available in the PitchBook Platform. To explore Spruce Biosciences‘s full profile, request access.

Request a free trial

Spruce Biosciences ESG

Risk Overview

Risk Rating

Updated August, 30, 2022

27.35 | Med Risk

Risk Scale

A lower score indicates better sustainability

Negl

0-10

Low

10-20

Med

20-30

High

30-40

Severe

40+

Exposure

Exposure refers to the extent to which a company is exposed to different material ESG issues

Management

Management is related to actions taken to manage ESG issues

Peers Analysis

Peer performance insights compare the company’s ESG performance to the performance of selected peers to help inform future ESG decisions and drive internal performance improvements.

Global

Covered Companies

of 14,912

Rank

Percentile

Pharmaceuticals

Industry

of 965

Rank

Percentile

Biotechnology

Subindustry

of 443

Rank

Percentile

To view Spruce Biosciences’s complete esg history, request access »

Spruce Biosciences FAQs

  • When was Spruce Biosciences founded?

    Spruce Biosciences was founded in 2016.

  • Where is Spruce Biosciences headquartered?

    Spruce Biosciences is headquartered in South San Francisco, CA.

  • What is the size of Spruce Biosciences?

    Spruce Biosciences has 25 total employees.

  • What industry is Spruce Biosciences in?

    Spruce Biosciences’s primary industry is Biotechnology.

  • Is Spruce Biosciences a private or public company?

    Spruce Biosciences is a Public company.

  • What is Spruce Biosciences’s stock symbol?

    The ticker symbol for Spruce Biosciences is SPRB.

  • What is the current stock price of Spruce Biosciences?

    As of 07-Jul-2025 the stock price of Spruce Biosciences is $0.07.

  • What is the current market cap of Spruce Biosciences?

    The current market capitalization of Spruce Biosciences is $2.96M.

  • What is Spruce Biosciences’s current revenue?

    The trailing twelve month revenue for Spruce Biosciences is $2.91M.

  • Who are Spruce Biosciences’s competitors?

    Crinetics Pharmaceuticals, Gelesis Holdings, and Ascendis Pharma are competitors of Spruce Biosciences.

  • What is Spruce Biosciences’s annual earnings per share (EPS)?

    Spruce Biosciences’s EPS for 12 months was -$1.32.

Data Transparency

  • Meet our data hygiene team

    Discover how our experts ensure you’re getting the most accurate financial data in the industry.

    Read blog »
  • How PitchBook sources data

    Our data operations team has logged over 3.5 million hours researching, organizing, and integrating the information you need most.

    Discover our process »