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Healthcare Private Equity Activity

Comprehensive data on healthcare private equity deal activity — updated weekly from PitchBook published reports

Healthcare services private equity dealmaking rose 9.6% year over year in 2025 to an estimated 747 transactions, even as total deal value declined 1.6% amid fewer closings and a meaningful Q4 pause. The aggregate story masks sharper subsector divergence: skilled nursing facilities, specialty pharmacy, hospitals and health systems, and intellectual and developmental disability practices led growth, while physician practice management deal count fell 18% behind steep pullbacks in gastroenterology, fertility, and ENT. Sponsors entering 2026 face a market defined less by where healthcare PE is active and more by which subsectors are entering their next consolidation cycle.

Healthcare PE at a Glance

747
+9.6% YoY
Healthcare services PE deals (2025)
−1.6%
Q4 pullback
Total deal value change YoY
−18%
regulatory friction
PPM deal count change
+57.1%
2026 recovery signal
PPM exit count change

Why It Matters

The Q4 pause in healthcare services dealmaking was driven by two specific forces. State-level regulatory friction in California and other states is reshaping how PPM transactions structure[1]. Uncertainty around 2026 premium subsidies is delaying deals that would otherwise close. Sponsors with active deal pipelines in oncology, musculoskeletal, and ambulatory surgical centers face a different competitive backdrop than those still pursuing dermatology and gastroenterology platforms.

Key takeaways

Deal activity

Volume up, value down — but not uniformly

An estimated 747 deals in 2025 marked a 9.6% YoY increase from a 2024 bottom. Total deal value fell 1.6% as Q4 saw a meaningful pause. The diverging volume-vs-value pattern reflects continued activity at the lower end of the deal-size distribution alongside selective restraint on larger transactions, with sponsors holding back on larger platform deals while continuing add-on activity.

Subsector divergence

PPM declined 18% while skilled nursing and specialty pharmacy led growth

Physician practice management deal count fell 18% in 2025, driven by gastroenterology, fertility, and ENT pullbacks. Skilled nursing facilities, specialty pharmacy, hospitals and health systems, and intellectual and developmental disability practices led growth. Healthcare PE in 2026 is multiple stories, not one.

Exit signal

PPM exits jumped 57.1% — a 2026 recovery signal

PPM exit count rose 57.1% in 2025. PitchBook frames this as an early signal that transaction volume could recover in 2026, especially in oncology and musculoskeletal. Sponsors with PPM platforms in those subsectors face a different exit calculus than the broader sector data suggests.

Companies & investors

The companies and investors below are active in this market. The italicized line under each is descriptive context — the entity's role in the dynamic this page is tracking.

Cencora
Strategic Acquirer

Acquired OneOncology for $7.4 billion in 2025 — a 2025 strategic transaction tracked by PitchBook in its Healthcare Services Report.

View Cencora profile →
Walgreens Boots Alliance
Strategic Seller

Sycamore Partners' $10 billion take-private of Walgreens was the largest strategic-to-PE healthcare transaction of 2025.

View Walgreens Boots Alliance profile →
Ascension
Health System / Strategic

Acquired AMSURG for $3.9 billion in 2025 — a 2025 ambulatory surgical center transaction with comp-set relevance.

View Ascension profile →
Lifepoint Health
Apollo PE-Backed Platform

Owned by Apollo Global Management. Continued joint venture growth strategy in 2025 with 70+ JVs across 30+ nonprofit partners.

View Lifepoint Health profile →

Featured research

The PitchBook reports and articles that source the data on this page.

Q1 2026

Q4 2025 Healthcare Services Report

Estimated 747 deals in 2025; PPM deal count down 18% but PPM exit count up 57.1% — early 2026 recovery signal in oncology and musculoskeletal.

Download report →
Q2 2025

Q1 2025 Healthcare Services PE Update

Strategic-to-PE consolidation including Sycamore's $10B take-private of Walgreens; subsector divergence emerging.

Download report →
2025

Healthcare PE dealmakers face pandemic déjà vu

Q3 2025 EV/EBITDA compressed into 8x–12x range and EV/sales between 0.5x and 1.2x — multiple compression amid market uncertainty.

Read article →

Get this data in PitchBook

This page surfaces 4 healthcare entities active in the 2025 cycle. PitchBook tracks the full healthcare PE deal universe — every closed and pending transaction, every PE-backed platform, and every reported add-on across the 747 deals identified in the Q4 2025 Healthcare Services Report.

Track healthcare PE deal flow in real time

Screen every healthcare deal by stage, subsector, sponsor, and deal type. Set alerts for activity in oncology, musculoskeletal, and other recovery-signaling categories.

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Map platform company ownership

Identify sponsor-backed platforms and their full add-on histories. Understand subsector concentration before entering a market.

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Benchmark valuations against comparable transactions

Compare EBITDA multiples and revenue multiples across healthcare deals. Q3 2025 data shows EV/EBITDA compressed into 8x–12x range and EV/sales between 0.5x and 1.2x.

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