Aptinyx Overview

  • Year Founded
  • 2015

Year Founded

  • Status
  • Private

  • Employees
  • 12

Employees

  • Latest Deal Type
  • 2PO

  • Latest Deal Amount
  • $30.5M

  • Investors
  • 2

Aptinyx General Information

Description

Aptinyx Inc is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel, proprietary, synthetic small molecules for the treatment of brain and nervous system disorders. Its pipeline products are NYX-2925, NYX-458, and NYX-783. NYX-2925 is a novel, oral, small-molecule NMDA receptor modulator in clinical development as a therapy for chronic pain. NYX-2925 works by enhancing synaptic plasticity, a mechanism uniquely suited to addressing chronic pain, and NYX-783 is an NMDA receptor modulating small molecule in clinical development as a therapy for post-traumatic stress disorder.

Contact Information

Website
www.aptinyx.com
Ownership Status
Privately Held (backing)
Financing Status
Formerly VC-backed
Corporate Office
  • 909 Davis Street
  • Suite 600
  • Evanston, IL 60201
  • United States
+1 (847)
Primary Industry
Drug Discovery
Vertical(s)
Corporate Office
  • 909 Davis Street
  • Suite 600
  • Evanston, IL 60201
  • United States
+1 (847)

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Aptinyx Valuation & Funding

Deal Type Date Amount Raised to Date Post-Val Status Stage
8. 2PO 13-Jan-2020 $30.5M Completed Generating Revenue
7. Secondary Transaction - Open Market Completed Generating Revenue
6. IPO 21-Jun-2018 Completed Clinical Trials - Phase 2
5. Early Stage VC (Series B) 18-Dec-2017 Completed Clinical Trials - Phase 2
4. Grant 01-Jan-2016 Completed Pre-Clinical Trials
3. Early Stage VC (Series A) 10-May-2016 Completed Pre-Clinical Trials
2. Seed Round 15-Sep-2015 Completed Startup
1. Spin-Off 28-Aug-2015 Completed Startup
To view Aptinyx’s complete valuation and funding history, request access »

Aptinyx Cap Table

Stock # of Shares
Authorized
Par Value Dividend Rate (%) Original
Issue Price
Liquidation Liquidation
Pref. Multiple
Conversion Price % Owned
Series B
Series A-2
Series A-1 151,772,701 $0.010000 $0.16 $0.16 1x $0.16 19.69%
To view Aptinyx’s complete cap table history, request access »

Aptinyx Comparisons

Description
Primary
Industry
HQ Location
Employees
Total Raised
Post Valuation
Last
Financing
Details
Aptinyx Inc is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization o
Drug Discovery
Evanston, IL
12 As of 2022

Wellesley Hills, MA
 

Burlington, MA
 
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Aptinyx Competitors (78)

One of Aptinyx’s 78 competitors is Climb Bio, a Formerly VC-backed company based in Wellesley Hills, MA.

Company Name Financing Status Location Employees Total Raised Last Financing Date/Type Last Financing Amount
Climb Bio Formerly VC-backed Wellesley Hills, MA
Neuphoria Therapeutics Formerly VC-backed Burlington, MA
CRISPR Therapeutics Formerly VC-backed Zug, Switzerland
Alzheon Venture Capital-Backed Framingham, MA
Orchard Therapeutics Formerly VC-backed London, United Kingdom
You’re viewing 5 of 78 competitors. Get the full list »

Aptinyx Patents

Aptinyx Recent Patent Activity

Publication ID Patent Title Status First Filing Date Technology (CPC) Citations
EP-4161517-A2 Spiro-lactam compounds and methods of treating viral infections Inactive 03-Jun-2020
CA-3184348-A1 Spiro-lactam compounds and methods of treating viral infections using the same Pending 03-Jun-2020
AU-2021284376-A1 Spiro-lactam compounds and methods of treating viral infections Pending 03-Jun-2020
US-20230210851-A1 Spiro-lactam compounds and methods of treating viral infections using the same Inactive 03-Jun-2020
AU-2020398840-A1 Methods of treating cognitive impairment associated with neurodegenerative disease Pending 04-Dec-2019 A61K31/438
To view Aptinyx’s complete patent history, request access »

Aptinyx Signals

Growth Rate

Weekly
Growth
Weekly Growth

Size Multiple

Median
Size Multiple

Key Data Points

Similarweb Unique Visitors

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Aptinyx Investors (2)

Investor Name Investor Type Holding Investor Since Participating Rounds
The National Institute on Aging (NIA) Government
Northwestern University University
To view Aptinyx’s complete investors history, request access »

Aptinyx ESG

Risk Overview

Risk Rating

Updated June, 13, 2021

25.2 | Med Risk

Risk Scale

A lower score indicates better sustainability

Negl

0-10

Low

10-20

Med

20-30

High

30-40

Severe

40+

Exposure

Exposure refers to the extent to which a company is exposed to different material ESG issues

Management

Management is related to actions taken to manage ESG issues

Peers Analysis

Peer performance insights compare the company’s ESG performance to the performance of selected peers to help inform future ESG decisions and drive internal performance improvements.

Global

Covered Companies

of 14,042

Rank

Percentile

Healthcare

Industry

of 577

Rank

Percentile

Medical Services

Subindustry

of 100

Rank

Percentile

To view Aptinyx’s complete esg history, request access »

Aptinyx FAQs

  • When was Aptinyx founded?

    Aptinyx was founded in 2015.

  • Where is Aptinyx headquartered?

    Aptinyx is headquartered in Evanston, IL.

  • What is the size of Aptinyx?

    Aptinyx has 12 total employees.

  • What industry is Aptinyx in?

    Aptinyx’s primary industry is Drug Discovery.

  • Is Aptinyx a private or public company?

    Aptinyx is a Private company.

  • What is Aptinyx’s current revenue?

    The current revenue for Aptinyx is .

  • How much funding has Aptinyx raised over time?

    Aptinyx has raised $268M.

  • Who are Aptinyx’s investors?

    The National Institute on Aging (NIA) and Northwestern University have invested in Aptinyx.

  • Who are Aptinyx’s competitors?

    Climb Bio, Neuphoria Therapeutics, CRISPR Therapeutics, Alzheon, and Orchard Therapeutics are some of the 78 competitors of Aptinyx.

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