Silence Therapeutics Overview

  • Year Founded
  • 1994

Year Founded

  • Status
  • Public

  • Employees
  • 88

Employees

  • Stock Symbol
  • SLNCF

Stock Symbol

  • Investments
  • 2

  • Share Price
  • $6.53
  • (As of Thursday Closing)

Silence Therapeutics General Information

Description

Silence Therapeutics PLC is a biotechnology company focused on discovering and developing novel molecules incorporating short-interfering ribonucleic acid or siRNA. Using its mRNAi GOLD platform, the company has generated siRNA product candidates both for its internal development pipeline as well as for out-licensed programs with third-party collaborators. Its wholly owned pipeline is focused on three therapeutic areas: cardiovascular disease, hematology, and rare diseases. The different product candidates in its pipeline are Divesiran (SLN124), a siRNA product candidate that has the potential to treat several hematological disorders; Zerlasiran (SLN360), being developed as a potential treatment to reduce cardiovascular issues; SLN-312; SLN-548; and multiple other programs.

Contact Information

Formerly Known As
Atugen
Ownership Status
Publicly Held
Financing Status
Formerly VC-backed
Corporate Office
  • 12 Hammersmith Grove
  • London W6 7AP
  • England, United Kingdom
+44 020
Primary Industry
Biotechnology
Other Industries
Drug Discovery
Pharmaceuticals
Stock Exchange
OTCM
Vertical(s)
Corporate Office
  • 12 Hammersmith Grove
  • London W6 7AP
  • England, United Kingdom
+44 020

Want detailed data on 11M+ companies?

What you see here scratches the surface

Request a free trial

Want to dig into this profile?

We’ll help you find what you need

Learn more

Silence Therapeutics Stock Performance

As of 12-Nov-2026, Silence Therapeutics’s stock price is $6.53. Its current market cap is $1.22B with 187M shares.

(As of Thursday Closing)

Stock Price Previous Close 52 wk Range Market Cap Shares Average Volume EPS
$6.53 $6.36 $1.06 - $6.53 $1.22B 187M 26.4K -$0.35

Silence Therapeutics Financials Summary

As of 30-Sep-2026, Silence Therapeutics has a trailing 12-month revenue of $456K.

In Thousands,
USD
TTM 30-Sep-2026 FY 2025 31-Dec-2025 FY 2024 31-Dec-2024 FY 2023 31-Dec-2023
EV 673,907 181,394 199,388 102,642
Revenue 456 559 43,258 31,643
EBITDA (91,526) (48,343) (54,454)
Net Income (51,421) (88,612) (45,309) (54,228)
Total Assets 281,498 131,442 202,635 119,448
Total Debt 87 160 117 346
Public Fundamental Data provided by Morningstar, Inc. disclaimer

Silence Therapeutics Valuation & Funding

Deal Type Date Amount Valuation/
EBITDA
Post-Val Status Debt

This information is available in the PitchBook Platform. To explore Silence Therapeutics‘s full profile, request access.

Request a free trial

Silence Therapeutics Comparisons

Description
Primary
Industry
HQ Location
Employees
Total Raised
Post Valuation
Last
Financing
Details
Silence Therapeutics PLC is a biotechnology company focused on discovering and developing novel molecules incorporating
Biotechnology
London, United Kingdom
88 As of 2025

Shelton, CT
 

Cambridge, MA
 
Add Comparison

PitchBook’s comparison feature gives you a side-by-side look at key metrics for similar companies. Personalize which data points you want to see and create visualizations instantly.

Request a free trial

Silence Therapeutics Competitors (82)

One of Silence Therapeutics’s 82 competitors is Nanoviricides, a Corporation company based in Shelton, CT.

Company Name Financing Status Location Employees Total Raised Last Financing Date/Type Last Financing Amount
Nanoviricides Corporation Shelton, CT
Alnylam Pharmaceuticals Formerly VC-backed Cambridge, MA
Amunix Pharmaceuticals Formerly PE-Backed South San Francisco, CA
BioCryst Pharmaceuticals Corporation Durham, NC
Novavax Corporation Gaithersburg, MD
You’re viewing 5 of 82 competitors. Get the full list »

Silence Therapeutics Patents

Silence Therapeutics Recent Patent Activity

Publication ID Patent Title Status First Filing Date Technology (CPC) Citations
WO-2011009082-A2 Compositions comprising human rhbdf1-modulating nucleic acids and methods of use Inactive 17-Jul-2009
WO-2011009082-A3 Compositions comprising human rhbdf1-modulating nucleic acids and methods of use Inactive 17-Jul-2009
WO-2011005980-A1 Novel heterobifunctional polyethylene glycol reagents, their preparation and uses thereof Inactive 09-Jul-2009
EP-2285959-A2 Compositions comprising cmyc sirna and methods of use thereof Inactive 11-Jun-2008
US-20110190375-A1 Compositions comprising cmyc sirna and methods of use thereof Inactive 11-Jun-2008 C12N15/1135
To view Silence Therapeutics’s complete patent history, request access »

Silence Therapeutics Signals

Growth Rate

Weekly
Growth
Weekly Growth

Size Multiple

Median
Size Multiple

Key Data Points

Similarweb Unique Visitors

Majestic Referring Domains

PitchBook’s non-financial metrics help you gauge a company’s traction and growth using web presence and social reach.

Request a free trial

Silence Therapeutics Investors

Investor Name Investor Type Holding Investor Since Participating Rounds Contact Info

This information is available in the PitchBook Platform. To explore Silence Therapeutics‘s full profile, request access.

Request a free trial

Silence Therapeutics Investments & Acquisitions (2)

Silence Therapeutics’s most recent deal was a PIPE with Arrowhead Pharmaceuticals for . The deal was made on 09-Jan-2017.

Company Name Deal Date Deal Type Deal Size Industry Lead Partner
Arrowhead Pharmaceuticals 09-Jan-2017 PIPE Biotechnology
Intradigm 05-Jan-2010 Merger/Acquisition Biotechnology
To view Silence Therapeutics’s complete investments and acquisitions history, request access »

Silence Therapeutics ESG

Peers Analysis

Peer performance insights compare the company’s ESG performance to the performance of selected peers to help inform future ESG decisions and drive internal performance improvements.

Global

Covered Companies

Rank

Percentile

Pharmaceuticals

Industry

Rank

Percentile

Biotechnology

Subindustry

Rank

Percentile

To view Silence Therapeutics’s complete esg history, request access »

Silence Therapeutics Exits (1)

Silence Therapeutics’s most recent exit was on 09-Jan-2017 from Arrowhead Pharmaceuticals. The exit was categorized as .

Company Name Exit Date Exit Type Exit Size Status Buyers
Arrowhead Pharmaceuticals 09-Jan-2017 Completed
To view Silence Therapeutics’s complete exits history, request access »

Silence Therapeutics FAQs

  • When was Silence Therapeutics founded?

    Silence Therapeutics was founded in 1994.

  • Where is Silence Therapeutics headquartered?

    Silence Therapeutics is headquartered in London, United Kingdom.

  • What is the size of Silence Therapeutics?

    Silence Therapeutics has 88 total employees.

  • What industry is Silence Therapeutics in?

    Silence Therapeutics’s primary industry is Biotechnology.

  • Is Silence Therapeutics a private or public company?

    Silence Therapeutics is a Public company.

  • What is Silence Therapeutics’s stock symbol?

    The ticker symbol for Silence Therapeutics is SLNCF.

  • What is the current stock price of Silence Therapeutics?

    As of 12-Nov-2026 the stock price of Silence Therapeutics is $6.53.

  • What is the current market cap of Silence Therapeutics?

    The current market capitalization of Silence Therapeutics is $1.22B.

  • What is Silence Therapeutics’s current revenue?

    The trailing twelve month revenue for Silence Therapeutics is $456K.

  • Who are Silence Therapeutics’s competitors?

    Nanoviricides, Alnylam Pharmaceuticals, Amunix Pharmaceuticals, BioCryst Pharmaceuticals, and Novavax are some of the 82 competitors of Silence Therapeutics.

  • What is Silence Therapeutics’s annual earnings per share (EPS)?

    Silence Therapeutics’s EPS for 12 months was -$0.35.

Data Transparency

  • Meet our data hygiene team

    Discover how our experts ensure you’re getting the most accurate financial data in the industry.

    Read more
  • How PitchBook sources data

    Our data operations team has logged over 3.5 million hours researching, organizing, and integrating the information you need most.

    Discover our process