The Column Group Overview

  • Investor Type
  • Venture Capital

  • Status
  • Active

  • Professionals
  • 27

Professionals

  • Investments
  • 127

  • Portfolio
  • 26

  • Exits
  • 29

Exits

The Column Group General Information

Company Description

Founded in 2007, The Column Group is a venture capital investment firm based in San Francisco, California. The firm prefers to invest in seed-stage and early-stage companies operating in healthcare, life sciences, oncology, drug discovery, and technology-based sectors in the United States. This firm is a Registered Investment Adviser (RIA).

Business Details

Year Founded
2007
Investor Status
Actively Seeking New Investments
Primary Investor Type
Venture Capital
Corporate Office
  • 1 Letterman Drive, Building D
  • Suite DM-900
  • San Francisco, CA 94129
  • United States
+1 (415)

The Column Group Investments (127)

Company Name Deal Date Deal Type Deal Size Industry Company Stage Lead Partner
Tortugas Neuroscience 01-Jun-2025 Early Stage VC Drug Discovery Startup
Neurona Therapeutics 28-Mar-2025 Drug Discovery Clinical Trials - Phase 2
Surrozen 24-Mar-2025 Drug Discovery Pre-Clinical Trials
Eikon Therapeutics 26-Feb-2025 Drug Discovery Generating Revenue
Cajal Neuroscience 04-Feb-2025 Drug Discovery Generating Revenue
Circle Pharma 10-Jan-2025 Drug Discovery Clinical Trials - Phase 1
A2 Bio 09-Jan-2025 Biotechnology Clinical Trials - Phase 1
Topo Therapeutics 31-Dec-2024 Drug Discovery Startup
RAPT Therapeutics 27-Dec-2024 PIPE Drug Discovery Generating Revenue
Judo Bio 07-Oct-2024 Early Stage VC Drug Discovery Pre-Clinical Trials
You’re viewing 10 of 127 investments. Get the full list »

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The Column Group Exits (29)

Company Name Exit Date Exit Type Exit Size
Ribon Therapeutics 05-Aug-2024 Out of Business
Escient Pharmaceuticals 30-May-2024
Carmot Therapeutics 26-Jan-2024
Sagimet Biosciences 14-Jul-2023
Effector Therapeutics 25-Aug-2021
Tenaya Therapeutics 30-Jul-2021
Constellation Pharmaceuticals 15-Jul-2021
Nurix Therapeutics 05-Mar-2021
ORIC Pharmaceuticals 13-Nov-2020 Public Investment 2nd Offering
Nurix Therapeutics 24-Jul-2020 IPO
You’re viewing 10 of 29 exits. Get the full list »

The Column Group Fund Performance

Fund Name Vintage Size Dry Powder DPI RVPI TVPI IRR

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The Column Group Investments by Industry, Year, and Region

Investments by Industry

Investments by Year

Investments by Region

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The Column Group FAQs

  • What is The Column Group?

    Founded in 2007, The Column Group is a venture capital investment firm based in San Francisco, California.

  • When was The Column Group founded?

    The Column Group was founded in 2007.

  • Where is The Column Group headquartered?

    The Column Group is headquartered in San Francisco, CA.

  • What is The Column Group's total asset value?

    The Column Group has around in total assets under management.

  • How many investments has The Column Group made?

    The Column Group has made 127 investments.

  • What has The Column Group invested in?

    The Column Group has made numerous investments in companies like Tortugas Neuroscience, Neurona Therapeutics, and Surrozen within the Drug Discovery industry.

  • What has The Column Group invested in recently?

    The Column Group's latest investment was on 01-Jun-2025 in Tortugas Neuroscience, a company within the Drug Discovery industry.

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