Caldera Therapeutics Overview

  • Year Founded
  • 2025

Year Founded

  • Status
  • Private

  • Employees
  • 10

Employees

  • Latest Deal Type
  • PIPE
  • (In Progress)

  • Latest Deal Amount
  • $278M

  • Investors
  • 7

Caldera Therapeutics General Information

Description

Caldera Therapeutics Inc is a clinical-stage biopharmaceutical company focused on the development of the investigational bispecific antibody CLD-423 for the treatment of inflammatory bowel disease (IBD) and other immune-mediated diseases. CLD-423 is designed to simultaneously inhibit two clinically validated inflammatory pathways, Tumor Necrosis Factor (TNF)-like ligand 1A (TL1A) and interleukin (IL)-23p19.

Contact Information

Ownership Status
Privately Held (backing)
Financing Status
Venture Capital-Backed
Corporate Office
  • 300 Technology Square
  • 8th Floor
  • Cambridge, MA 02139
  • United States
Primary Industry
Drug Discovery
Other Industries
Biotechnology
Vertical(s)
Corporate Office
  • 300 Technology Square
  • 8th Floor
  • Cambridge, MA 02139
  • United States

Caldera Therapeutics Timeline

2026
Date FoundedFinancing RoundCaptured Employee CountEstimated Employee Growth

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Caldera Therapeutics Valuation & Funding

Deal Type Date Amount Raised to Date Post-Val Status Stage
4. PIPE 29-Jul-2026 $278M In Progress Clinical Trials - Phase 1
3. Reverse Merger 29-Jul-2026 Announced Clinical Trials - Phase 1
2. Early Stage VC (Series A1) 08-Jan-2026 $37.5M $112M Completed Clinical Trials - Phase 1
1. Early Stage VC (Series A) 01-Apr-2025 $75M $75M Completed Pre-Clinical Trials
To view Caldera Therapeutics’s complete valuation and funding history, request access »

Caldera Therapeutics Cap Table

Stock # of Shares
Authorized
Par Value Dividend Rate (%) Original
Issue Price
Liquidation Liquidation
Pref. Multiple
Conversion Price % Owned
Series A1
Series A
To view Caldera Therapeutics’s complete cap table history, request access »

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Caldera Therapeutics Signals

Growth Rate

Weekly
Growth
Weekly Growth

Size Multiple

Median
Size Multiple

Key Data Points

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Caldera Therapeutics Investors (7)

Investor Name Investor Type Holding Investor Since Participating Rounds
Janus Henderson Investors Asset Manager Minority
LifeSci Venture Partners Corporate Venture Capital Minority
Omega Funds Venture Capital Minority
Wellington Management Asset Manager Minority
Atlas Venture Venture Capital Minority
You’re viewing 5 of 7 investors. Get the full list »

Caldera Therapeutics Acquisitions (1)

Caldera Therapeutics’s most recent deal was a Merger/Acquisition with Synlogic. The deal was made on 29-Jul-2026.

Company Name Deal Date Deal Type Deal Size Industry Lead Partner
Synlogic 29-Jul-2026 Merger/Acquisition Drug Discovery
To view Caldera Therapeutics’s complete acquisitions history, request access »

Caldera Therapeutics FAQs

  • When was Caldera Therapeutics founded?

    Caldera Therapeutics was founded in 2025.

  • Where is Caldera Therapeutics headquartered?

    Caldera Therapeutics is headquartered in Cambridge, MA.

  • What is the size of Caldera Therapeutics?

    Caldera Therapeutics has 10 total employees.

  • What industry is Caldera Therapeutics in?

    Caldera Therapeutics’s primary industry is Drug Discovery.

  • Is Caldera Therapeutics a private or public company?

    Caldera Therapeutics is a Private company.

  • What is Caldera Therapeutics’s current revenue?

    The current revenue for Caldera Therapeutics is .

  • How much funding has Caldera Therapeutics raised over time?

    Caldera Therapeutics has raised $112M.

  • Who are Caldera Therapeutics’s investors?

    Janus Henderson Investors, LifeSci Venture Partners, Omega Funds, Wellington Management, and Atlas Venture are 5 of 7 investors who have invested in Caldera Therapeutics.

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