Actuate Therapeutics Overview

  • Year Founded
  • 2015

Year Founded

  • Status
  • Public

  • Employees
  • 16

Employees

  • Stock Symbol
  • ACTU

Stock Symbol

  • Share Price
  • $0.31
  • (As of Thursday Closing)

Actuate Therapeutics General Information

Description

Actuate Therapeutics Inc is a clinical stage biopharmaceutical company focused on developing therapies for the treatment of high impact, difficult to treat cancers through the inhibition of glycogen synthase kinase-3 (GSK-3). It is developing elraglusib (formerly 9-ING-41), a small molecule that is designed to enter cancer cells and block the function of the enzyme GSK-3B, a master regulator of complex biological signaling cascades, including those mediated by oncogenes, that lead to tumor cell survival, growth, migration, and invasion.

Contact Information

Formerly Known As
Apotheca Therapeutics
Ownership Status
Publicly Held
Financing Status
Formerly VC-backed
Corporate Office
  • 1751 River Run
  • Suite 400
  • Fort Worth, TX 76107
  • United States
+1 (847)
Primary Industry
Drug Discovery
Other Industries
Biotechnology
Stock Exchange
NAS
Vertical(s)
Corporate Office
  • 1751 River Run
  • Suite 400
  • Fort Worth, TX 76107
  • United States
+1 (847)

Actuate Therapeutics Timeline

2023202420252026
Financing RoundCaptured Employee CountEstimated Employee Growth

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Actuate Therapeutics Stock Performance

As of 12-Nov-2026, Actuate Therapeutics’s stock price is $0.31. Its current market cap is $16.3M with 55M shares.

(As of Thursday Closing)

Stock Price Previous Close 52 wk Range Market Cap Shares Average Volume EPS
$0.31 $0.30 $0.29 - $7.90 $16.3M 55M 427K -$0.87

Actuate Therapeutics Financials Summary

As of 30-Jun-2026, Actuate Therapeutics has a trailing 12-month revenue of null.

In Thousands,
USD
TTM 30-Jun-2026 FY 2025 31-Dec-2025 FY 2024 31-Dec-2024 FY 2023 31-Dec-2023
EV 28,473 125,324 141,948
Revenue 0 0 0 0
EBITDA (20,773) (22,495) (27,489) (25,054)
Net Income (20,454) (22,228) (27,285) (24,745)
Total Assets 5,199 14,036 9,318 2,996
Total Debt 0 0 0 988
Public Fundamental Data provided by Morningstar, Inc. disclaimer

Actuate Therapeutics Valuation & Funding

Deal Type Date Amount Valuation/
EBITDA
Post-Val Status Debt

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Actuate Therapeutics Cap Table

Stock # of Shares
Authorized
Par Value Dividend Rate (%) Original
Issue Price
Liquidation Liquidation
Pref. Multiple
Conversion
Price
% Owned

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Actuate Therapeutics Comparisons

Description
Primary
Industry
HQ Location
Employees
Total Raised
Post Valuation
Last
Financing
Details
Actuate Therapeutics Inc is a clinical stage biopharmaceutical company focused on developing therapies for the treatment
Drug Discovery
Fort Worth, TX
16 As of 2026

Cambridge, MA
 

Santa Monica, CA
 
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Actuate Therapeutics Competitors (62)

One of Actuate Therapeutics’s 62 competitors is Marengo Therapeutics, a Venture Capital-Backed company based in Cambridge, MA.

Company Name Financing Status Location Employees Total Raised Last Financing Date/Type Last Financing Amount
Marengo Therapeutics Venture Capital-Backed Cambridge, MA
Kite Pharma Formerly VC-backed Santa Monica, CA
Carisma Therapeutics Formerly VC-backed Philadelphia, PA
Inovio Pharmaceuticals Corporation Plymouth Meeting, PA
CytomX Therapeutics Formerly VC-backed South San Francisco, CA
You’re viewing 5 of 62 competitors. Get the full list »

Actuate Therapeutics Patents

Actuate Therapeutics Recent Patent Activity

Publication ID Patent Title Status First Filing Date Technology (CPC) Citations
WO-2026128597-A1 Pharmaceutical compositions comprising combinations of elaraglusib and other therapeutic agents for the treatment of cancer Pending 13-Dec-2024
WO-2026107416-A1 Single dosage forms containing elraglusib and at least one other active ingredient Pending 18-Nov-2024
WO-2025221600-A1 Biomarkers for use in pancreatic cancer treatment Pending 15-Apr-2024
WO-2025221600-A9 Biomarkers for use in pancreatic cancer treatment Pending 15-Apr-2024
WO-2025183906-A1 Biomarkers for use in cancer therapy Pending 01-Mar-2024 A61P35/00
To view Actuate Therapeutics’s complete patent history, request access »

Actuate Therapeutics Signals

Growth Rate

Weekly
Growth
Weekly Growth

Size Multiple

Median
Size Multiple

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Actuate Therapeutics ESG

Peers Analysis

Peer performance insights compare the company’s ESG performance to the performance of selected peers to help inform future ESG decisions and drive internal performance improvements.

Global

Covered Companies

Rank

Percentile

Pharmaceuticals

Industry

Rank

Percentile

Biotechnology

Subindustry

Rank

Percentile

To view Actuate Therapeutics’s complete esg history, request access »

Actuate Therapeutics FAQs

  • When was Actuate Therapeutics founded?

    Actuate Therapeutics was founded in 2015.

  • Where is Actuate Therapeutics headquartered?

    Actuate Therapeutics is headquartered in Fort Worth, TX.

  • What is the size of Actuate Therapeutics?

    Actuate Therapeutics has 16 total employees.

  • What industry is Actuate Therapeutics in?

    Actuate Therapeutics’s primary industry is Drug Discovery.

  • Is Actuate Therapeutics a private or public company?

    Actuate Therapeutics is a Public company.

  • What is Actuate Therapeutics’s stock symbol?

    The ticker symbol for Actuate Therapeutics is ACTU.

  • What is the current stock price of Actuate Therapeutics?

    As of 12-Nov-2026 the stock price of Actuate Therapeutics is $0.31.

  • What is the current market cap of Actuate Therapeutics?

    The current market capitalization of Actuate Therapeutics is $16.3M.

  • Who are Actuate Therapeutics’s competitors?

    Marengo Therapeutics, Kite Pharma, Carisma Therapeutics, Inovio Pharmaceuticals, and CytomX Therapeutics are some of the 62 competitors of Actuate Therapeutics.

  • What is Actuate Therapeutics’s annual earnings per share (EPS)?

    Actuate Therapeutics’s EPS for 12 months was -$0.87.

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