HotSpot Therapeutics Overview

  • Year Founded
  • 2017

Year Founded

  • Status
  • Private

  • Employees
  • 65

Employees

  • Latest Deal Type
  • 2ndary - Private

  • Investors
  • 17

HotSpot Therapeutics General Information

Description

Developer of a therapeutic platform designed for allosteric drug discovery. The company's platform helps to identify hotspots and locate pathway treatments for cancer, metabolic, and rare diseases as well as leverages a database of hotspot structures, harnessing the power of data science in its multidisciplinary approach to drug discovery, enabling patients to get a conventional treatment against various diseases.

Contact Information

Ownership Status
Privately Held (backing)
Financing Status
Venture Capital-Backed
Corporate Office
  • One Design Center Place
  • Suite 19-600
  • Boston, MA 02210
  • United States
+1 (617)
Primary Industry
Drug Discovery
Other Industries
Biotechnology
Corporate Office
  • One Design Center Place
  • Suite 19-600
  • Boston, MA 02210
  • United States
+1 (617)

HotSpot Therapeutics Timeline

2022202320242025
Financing RoundCaptured Employee CountEstimated Employee Growth

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HotSpot Therapeutics Valuation & Funding

Deal Type Date Amount Raised to Date Post-Val Status Stage
5. Secondary Transaction - Private 01-Nov-2023 Completed Clinical Trials - Phase 1
4. Later Stage VC (Series C) 16-Nov-2021 Completed Clinical Trials - Phase 1
3. Early Stage VC (Series B) 21-May-2020 Completed Clinical Trials - Phase 1
2. Early Stage VC (Series A) 17-Jul-2018 $40M $45M Completed Pre-Clinical Trials
1. Seed Round 23-Feb-2017 $5M $5M Completed Pre-Clinical Trials
To view HotSpot Therapeutics’s complete valuation and funding history, request access »

HotSpot Therapeutics Cap Table

Stock # of Shares
Authorized
Par Value Dividend Rate (%) Original
Issue Price
Liquidation Liquidation
Pref. Multiple
Conversion Price % Owned
Series C
Series B
Series A 10,000,000 $0.000100 6% $2 $2 1x $2 10.8%
Seed 5,000,000 $0.000100 6% $1 $1 1x $1 5.4%
To view HotSpot Therapeutics’s complete cap table history, request access »

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Opportunity Score

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HotSpot Therapeutics Comparisons

Description
Primary
Industry
HQ Location
Employees
Total Raised
Post Valuation
Last
Financing
Details
Developer of a therapeutic platform designed for allosteric drug discovery. The company's platform helps to identify hot
Drug Discovery
Boston, MA
65 As of 2025

Boston, MA
 

Middleton, WI
 
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HotSpot Therapeutics Competitors (45)

One of HotSpot Therapeutics’s 45 competitors is ROME Therapeutics, a Venture Capital-Backed company based in Boston, MA.

Company Name Financing Status Location Employees Total Raised Last Financing Date/Type Last Financing Amount
ROME Therapeutics Venture Capital-Backed Boston, MA
Centrose Venture Capital-Backed Middleton, WI
Allorion Therapeutics Venture Capital-Backed Natick, MA
Antabio Venture Capital-Backed Labege, France
NexImmune Formerly VC-backed Gaithersburg, MD
You’re viewing 5 of 45 competitors. Get the full list »

HotSpot Therapeutics Patents

HotSpot Therapeutics Recent Patent Activity

Publication ID Patent Title Status First Filing Date Technology (CPC) Citations
US-20240150321-A1 Pyrazolylsulfonamide compounds and their use in therapy Pending 26-Aug-2022
US-20240150365-A1 Pyridinylsulfonamide compounds and their use in therapy Pending 26-Aug-2022
AU-2023329399-A1 Pyrazolylsulfonamide compounds and their use in therapy Pending 26-Aug-2022
AU-2023305605-A1 Solid forms of a triazine derivative as cbl-b modulator Pending 12-Jul-2022
AU-2023306375-A1 Cbl-b inhibitors and anti-pd1/anti-pd-l1 for use in the treatment of cancer Pending 12-Jul-2022 A61K31/4545
To view HotSpot Therapeutics’s complete patent history, request access »

HotSpot Therapeutics Signals

Growth Rate

Weekly
Growth
Weekly Growth

Size Multiple

Median
Size Multiple

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HotSpot Therapeutics Investors (17)

Investor Name Investor Type Holding Investor Since Participating Rounds
Aberdeen Asset Manager Minority
CaaS Capital Management Hedge Fund Minority
Monashee Investment Management Hedge Fund Minority
Nan Fung Life Sciences Venture Capital Minority
Pavilion Capital PE/Buyout Minority
You’re viewing 5 of 17 investors. Get the full list »

HotSpot Therapeutics Acquisitions (1)

HotSpot Therapeutics’s most recent deal was a Merger/Acquisition with Macroceutics. The deal was made on 23-Aug-2019.

Company Name Deal Date Deal Type Deal Size Industry Lead Partner
Macroceutics 23-Aug-2019 Merger/Acquisition Biotechnology
To view HotSpot Therapeutics’s complete acquisitions history, request access »

HotSpot Therapeutics FAQs

  • When was HotSpot Therapeutics founded?

    HotSpot Therapeutics was founded in 2017.

  • Where is HotSpot Therapeutics headquartered?

    HotSpot Therapeutics is headquartered in Boston, MA.

  • What is the size of HotSpot Therapeutics?

    HotSpot Therapeutics has 65 total employees.

  • What industry is HotSpot Therapeutics in?

    HotSpot Therapeutics’s primary industry is Drug Discovery.

  • Is HotSpot Therapeutics a private or public company?

    HotSpot Therapeutics is a Private company.

  • What is HotSpot Therapeutics’s current revenue?

    The current revenue for HotSpot Therapeutics is .

  • How much funding has HotSpot Therapeutics raised over time?

    HotSpot Therapeutics has raised $210M.

  • Who are HotSpot Therapeutics’s investors?

    Aberdeen, CaaS Capital Management, Monashee Investment Management, Nan Fung Life Sciences, and Pavilion Capital are 5 of 17 investors who have invested in HotSpot Therapeutics.

  • Who are HotSpot Therapeutics’s competitors?

    ROME Therapeutics, Centrose, Allorion Therapeutics, Antabio, and NexImmune are some of the 45 competitors of HotSpot Therapeutics.

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