Profluent Overview

  • Year Founded
  • 2022

Year Founded

  • Status
  • Private

  • Employees
  • 50

Employees

  • Latest Deal Type
  • Series B

  • Latest Deal Amount
  • $106M

  • Investors
  • 10

Profluent General Information

Description

Developer of artificial intelligence-driven models designed to create and validate novel proteins for biomedicine. The company's platform leverages deep generative models trained on billions of biological sequences, enabling the healthcare industry to optimize across diverse functional attributes in enzymes, antibodies, gene editors, and peptides.

Contact Information

Website
www.profluent.bio
Ownership Status
Privately Held (backing)
Financing Status
Venture Capital-Backed
Corporate Office
  • 1480 64th Street
  • Emeryville, CA 94608
  • United States
Primary Industry
Biotechnology
Vertical(s)
Big Data, Digital Health, Artificial Intelligence & Machine Learning, HealthTech, Life Sciences
Corporate Office
  • 1480 64th Street
  • Emeryville, CA 94608
  • United States

Profluent Timeline

2023202420252026
Financing RoundCaptured Employee CountEstimated Employee Growth

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Profluent Valuation & Funding

Deal Type Date Amount Raised to Date Post-Val Status Stage
3. Early Stage VC (Series B) 19-Nov-2025 $106M Completed Generating Revenue
2. Early Stage VC 21-Mar-2024 Completed Generating Revenue
1. Seed Round 26-Jan-2023 $9M $9M Completed Generating Revenue
To view Profluent’s complete valuation and funding history, request access »

Profluent Cap Table

Stock # of Shares
Authorized		 Par Value Dividend Rate (%) Original
Issue Price		 Liquidation Liquidation
Pref. Multiple		 Conversion Price % Owned
Series B
Series A
Seed 2,880,000 $0.000010 8% $3.12 $3.12 1x $3.12 19.63%
To view Profluent’s complete cap table history, request access »

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Profluent Comparisons

Description
Primary
Industry
HQ Location
Employees
Total Raised
Post Valuation
Last
Financing
Details
Developer of artificial intelligence-driven models designed to create and validate novel proteins for biomedicine. The c
Biotechnology
Emeryville, CA
50 As of 2026

Seattle, WA
 

Monrovia, CA
 
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Profluent Competitors (4)

One of Profluent’s 4 competitors is Arzeda, a Venture Capital-Backed company based in Seattle, WA.

Company Name Financing Status Location Employees Total Raised Last Financing Date/Type Last Financing Amount
Arzeda Venture Capital-Backed Seattle, WA
Terray Therapeutics Venture Capital-Backed Monrovia, CA
AI Proteins Venture Capital-Backed Boston, MA
Valitor (Biotechnology) Venture Capital-Backed Berkeley, CA
To view Profluent’s complete competitors history, request access »

Profluent Patents

  • 11

    Total Documents Applications and Grants

  • Total Patents Families

  • 3

    Granted

  • 7

    Pending

  • Expiring in next 12 mo

Profluent Recent Patent Activity

Publication ID Patent Title Status First Filing Date Technology (CPC) Citations
WO-2026143219-A1 Systems and methods for determining and engineering pam specificity of cas proteins Pending 26-Dec-2024
WO-2026030717-A1 Systems and methods for protein design Pending 01-Aug-2024
AU-2025214889-A1 Nucleases and compositions, systems, and methods thereof Pending 31-Jan-2024
US-12123016-B1 Nucleases and compositions, systems, and methods thereof Active 31-Jan-2024
US-20250243515-A1 Nucleases and compositions, systems, and methods thereof Pending 31-Jan-2024 C12N15/907
To view Profluent’s complete patent history, request access »

Profluent Signals

Growth Rate

Weekly
Growth
Weekly Growth

Size Multiple

Median
Size Multiple

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Profluent Investors (10)

Investor Name Investor Type Holding Investor Since Participating Rounds
Altimeter Capital Management Venture Capital Minority
Bezos Expeditions Family Office Minority
Angel (individual) Minority
QB3 Accelerator/Incubator Minority
Spark Capital Venture Capital Minority
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Profluent FAQs

  • When was Profluent founded?

    Profluent was founded in 2022.

  • Where is Profluent headquartered?

    Profluent is headquartered in Emeryville, CA.

  • What is the size of Profluent?

    Profluent has 50 total employees.

  • What industry is Profluent in?

    Profluent’s primary industry is Biotechnology.

  • Is Profluent a private or public company?

    Profluent is a Private company.

  • What is the current valuation of Profluent?

    The current valuation of Profluent is .

  • What is Profluent’s current revenue?

    The current revenue for Profluent is .

  • How much funding has Profluent raised over time?

    Profluent has raised $150M.

  • Who are Profluent’s investors?

    Altimeter Capital Management, Bezos Expeditions, , QB3, and Spark Capital are 5 of 10 investors who have invested in Profluent.

  • Who are Profluent’s competitors?

    Arzeda, Terray Therapeutics, AI Proteins, and Valitor (Biotechnology) are competitors of Profluent.

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