Palo Santo Overview
- Investor Type
-
Venture Capital
- Status
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Active
- Professionals
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5
- Investments
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45
- Portfolio
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29
- Exits
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10
Palo Santo General Information
Company Description
Founded in 2020, Palo Santo is a venture capital firm based in Chicago, Illinois. The firm is investing in breakthrough mental health and neurological therapeutics, spanning differentiated CNS targets, next-generation psychedelic medicines, and cutting-edge research tools that advance translational neuroscience.
Business Details
Website
palosanto.vcYear Founded
Investor Status
Primary Investor Type
Corporate Office
- Chicago, IL
- United States
Palo Santo Investments (45)
| Company Name | Deal Date | Deal Type | Deal Size | Industry | Company Stage | Lead Partner |
|---|---|---|---|---|---|---|
| Tempero Bio | 05-Nov-2025 | Later Stage VC | Drug Discovery | Clinical Trials - Phase 2 | ||
| Beacon Biosignals | 01-Oct-2025 | Therapeutic Devices | Generating Revenue | |||
| Psy Therapeutics | 09-Sep-2025 | Drug Discovery | Pre-Clinical Trials | |||
| Modulate Bio | 18-Jul-2025 | Drug Discovery | Pre-Clinical Trials | |||
| Syndeio Biosciences | 27-May-2025 | Drug Discovery | Clinical Trials - Phase 2 | |||
| Blackbox Bio | 01-Mar-2025 | Discovery Tools (Healthcare) | Generating Revenue | |||
| Pangea Bio | 28-Oct-2024 | Drug Discovery | Clinical Trials - Phase 1 | |||
| Xylo Bio | 20-Aug-2024 | Drug Discovery | Pre-Clinical Trials | |||
| Reunion Neuroscience | 25-Jan-2024 | PE Growth/Expansion | Drug Discovery | Clinical Trials - Phase 2 | ||
| BRC Therapeutics | 09-Aug-2023 | Later Stage VC | Drug Discovery | Clinical Trials - Phase 2 |
Palo Santo Exits (10)
| Company Name | Exit Date | Exit Type | Exit Size |
|---|---|---|---|
| Neuphoria Therapeutics | 28-Jul-2026 | Merger/Acquisition | |
| Transcend Therapeutics | 12-Jun-2026 | ||
| Beckley Psytech | 03-Jun-2025 | ||
| Ocean Bio | 14-Jun-2024 | ||
| Cybin | 04-Aug-2023 | ||
| Eleusis | 20-Oct-2022 | ||
| Awakn Life Sciences | 23-Jun-2021 | ||
| AtaiBeckley | 18-Jun-2021 | ||
| Reunion Neuroscience | 17-Mar-2021 | Public Investment 2nd Offering | |
| Bright Minds | 08-Feb-2021 | IPO |
Palo Santo Investments by Industry, Year, and Region
Investments by Industry
Investments by Year
Investments by Region
Palo Santo Co-Investors (117)
| Name | With | Exits | Lead Partner | Series | Industry |
|---|---|---|---|---|---|
| Gaingels | 5 |
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| JLS Fund |
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| PsyMed Ventures |
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| Calm Ventures |
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| Iter Investments |
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Palo Santo FAQs
-
What is Palo Santo?
Founded in 2020, Palo Santo is a venture capital firm based in Chicago, Illinois.
-
When was Palo Santo founded?
Palo Santo was founded in 2020.
-
Where is Palo Santo headquartered?
Palo Santo is headquartered in Chicago, IL.
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What is Palo Santo's total asset value?
Palo Santo has around in total assets under management.
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How many investments has Palo Santo made?
Palo Santo has made 45 investments.
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What has Palo Santo invested in?
Palo Santo has made numerous investments in companies like Tempero Bio, Beacon Biosignals, and Psy Therapeutics within the Drug Discovery and Therapeutic Devices industries.
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What has Palo Santo invested in recently?
Palo Santo's latest investment was on 05-Nov-2025 in Tempero Bio, a company within the Drug Discovery industry.
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