Lightstone Ventures Overview
- Investor Type
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Venture Capital
- Status
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Active
- Professionals
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9
- Investments
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109
- Portfolio
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31
- Exits
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42
Lightstone Ventures General Information
Company Description
Founded in 2012, Lightstone Ventures is a venture capital firm based in Portola Valley, California. The firm prefers to invest in early-stage and late-stage healthcare, life science, medical devices, therapeutic, and novel biopharmaceutical companies based in Europe and Australia. This firm is a Registered Investment Adviser (RIA).
Business Details
Website
www.lightstonevc.comYear Founded
Investor Status
Trade Association
Primary Investor Type
Corporate Office
- 3270 Alpine Road
- Portola Valley, CA 94028
- United States
Lightstone Ventures Investments (109)
| Company Name | Deal Date | Deal Type | Deal Size | Industry | Company Stage | Lead Partner |
|---|---|---|---|---|---|---|
| PsiThera | 10-Nov-2026 | Early Stage VC | Drug Discovery | Startup | ||
| Crystalys Therapeutics | 22-Jul-2026 | Drug Discovery | Clinical Trials - Phase 3 | |||
| Alchemab Therapeutics | 09-Jul-2026 | Drug Discovery | Clinical Trials - Phase 1 | |||
| Cerevance | 23-Apr-2026 | Drug Discovery | Clinical Trials - Phase 3 | |||
| PsiThera | 10-Dec-2025 | Drug Discovery | Startup | |||
| Crystalys Therapeutics | 30-Sep-2025 | Drug Discovery | Clinical Trials - Phase 3 | |||
| Reprieve Cardiovascular | 17-Sep-2025 | Biotechnology | Clinical Trials - Phase 2 | |||
| ProVerum | 21-Aug-2025 | Therapeutic Devices | Generating Revenue | |||
| Allay Therapeutics | 05-Jun-2025 | Later Stage VC | Drug Discovery | Clinical Trials - Phase 2 | ||
| Mavericks Endo | 01-Jun-2025 | Early Stage VC | Biotechnology | Out of Business |
Lightstone Ventures Exits (42)
| Company Name | Exit Date | Exit Type | Exit Size |
|---|---|---|---|
| MediSix Therapeutics | 13-Aug-2026 | Merger/Acquisition | |
| Parvalis Therapeutics | 06-May-2026 | ||
| Astria Therapeutics | 23-Jan-2026 | ||
| Mersana Therapeutics | 06-Jan-2026 | ||
| Mavericks Endo | 31-Dec-2025 | ||
| Shoulder Innovations | 31-Jul-2025 | ||
| Locanabio | 01-Mar-2024 | ||
| Ligature Therapeutics | 19-Mar-2023 | ||
| Tizona Therapeutics | 01-Dec-2022 | Secondary Transaction - Private | |
| Vigil Neuro | 07-Jan-2022 | IPO |
Lightstone Ventures Fund Performance
| Fund Name | Vintage | Size | Dry Powder | DPI | RVPI | TVPI | IRR |
|---|
Lightstone Ventures Investments by Industry, Year, and Region
Investments by Industry
Investments by Year
Investments by Region
Lightstone Ventures Co-Investors (160)
| Name | With | Exits | Lead Partner | Series | Industry |
|---|---|---|---|---|---|
| Gilde Healthcare | 5 |
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| GV |
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| New Enterprise Associates |
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| SV Health Investors |
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| Santé Ventures |
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Lightstone Ventures FAQs
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What is Lightstone Ventures?
Founded in 2012, Lightstone Ventures is a venture capital firm based in Portola Valley, California.
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When was Lightstone Ventures founded?
Lightstone Ventures was founded in 2012.
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Where is Lightstone Ventures headquartered?
Lightstone Ventures is headquartered in Portola Valley, CA.
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What is Lightstone Ventures's total asset value?
Lightstone Ventures has around in total assets under management.
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How many investments has Lightstone Ventures made?
Lightstone Ventures has made 109 investments.
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What has Lightstone Ventures invested in?
Lightstone Ventures has made numerous investments in companies like PsiThera, Crystalys Therapeutics, and Alchemab Therapeutics within the Drug Discovery industry.
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What has Lightstone Ventures invested in recently?
Lightstone Ventures's latest investment was on 10-Nov-2026 in PsiThera, a company within the Drug Discovery industry.
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