MainSheet Ventures Overview

  • Investor Type
  • Venture Capital

  • Status
  • Active

  • Professionals
  • 2

Professionals

  • Investments
  • 20

  • Portfolio
  • 19

  • Exits
  • 1

Exits

MainSheet Ventures General Information

Company Description

Founded in 2024, MainSheet Ventures is a venture capital investment firm based in Amherst, New York. The firm prefers to invest in companies operating in the healthcare, med tech/devices, robotics, artificial intelligence, software, and consumer brands sectors.

Business Details

Year Founded
2024
Investor Status
Actively Seeking New Investments
Primary Investor Type
Venture Capital
Corporate Office
  • 4357 Harlem Road
  • Amherst, NY 14226
  • United States

MainSheet Ventures Investments (20)

Company Name Deal Date Deal Type Deal Size Industry Company Stage Lead Partner
2TheBarn 01-May-2026 Later Stage VC Social/Platform Software Out of Business
Phantom Neuro 21-Nov-2025 Therapeutic Devices Generating Revenue
HealthScope (Healthcare Technology Systems) 01-Nov-2025 Other Healthcare Technology Systems Stealth
Psyonic 10-Oct-2025 Therapeutic Devices Generating Revenue
Bolt.Healthcare 01-Oct-2025 Enterprise Systems (Healthcare) Generating Revenue
Brand 5683 01-Oct-2025 Clothing Generating Revenue
Babyark 25-Aug-2025 Other Consumer Durables Generating Revenue
Wild West Systems 07-Aug-2025 Aerospace and Defense Startup
Figure 22-May-2025 Later Stage VC Other Hardware Generating Revenue
Ripple 01-Jan-2025 Later Stage VC Other Financial Services Generating Revenue
You’re viewing 10 of 20 investments. Get the full list »

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MainSheet Ventures Exits (1)

Company Name Exit Date Exit Type Exit Size
2TheBarn 27-May-2026
To view MainSheet Ventures’s complete exits history, request access »

MainSheet Ventures Investments by Industry, Year, and Region

Investments by Industry

Investments by Year

Investments by Region

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MainSheet Ventures FAQs

  • What is MainSheet Ventures?

    Founded in 2024, MainSheet Ventures is a venture capital investment firm based in Amherst, New York.

  • When was MainSheet Ventures founded?

    MainSheet Ventures was founded in 2024.

  • Where is MainSheet Ventures headquartered?

    MainSheet Ventures is headquartered in Amherst, NY.

  • How many investments has MainSheet Ventures made?

    MainSheet Ventures has made 20 investments.

  • What has MainSheet Ventures invested in?

    MainSheet Ventures has made numerous investments in companies like 2TheBarn, Phantom Neuro, and HealthScope (Healthcare Technology Systems) within the Social/Platform Software, Therapeutic Devices, and Healthcare Technology Systems industries.

  • What has MainSheet Ventures invested in recently?

    MainSheet Ventures's latest investment was on 01-May-2026 in 2TheBarn, a company within the Social/Platform Software industry.

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